Modified Nucleic Acids by Kazuhiko Nakatani

Modified Nucleic Acids



Download Modified Nucleic Acids

Modified Nucleic Acids Kazuhiko Nakatani ebook
ISBN: 9783319271095
Page: 330
Format: pdf
Publisher: Springer International Publishing


The study of conformationally restricted carbohydrate modified nucleic acids has given new insights into the concept of the antisense technology. Locked 2′-Deoxy-2′,4′-Difluororibo Modified Nucleic Acids: Thermal Stability , Structural Studies, and siRNA Activity. Recently, we discovered that short peptide nucleic acids (PNA) bind strongly of RNA could be enhanced by α-guanidine modification of PNA. This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on. Doi: 10.1007/978-1-4939-2763-0_12. Nucleic acid aging and age-related dysfunction in gene expression. The NIH announces a novel method for fast, simple, and accurate detection of nucleic acids outside the modern laboratory. Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents Open. ( nonenzymatic that nucleic acids also can undergo nonenzymatic modification by sugars. A new thermodynamic database for normal and modified nucleic acids has been developed.





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